calixar.com-membrane proteins | calixar - membrane proteins isolation, extraction and produc

Données techniques du calixar.com

Geo IP vous fournit comme la latitude, la longitude et l'ISP (Internet Service Provider) etc. informations. Notre service GeoIP a trouvé l'hôte calixar.com.Actuellement, hébergé dans France et son fournisseur de services est OVH SAS .

Latitude:	50.69421005249
Longitude:	3.1745600700378
Pays:	France (fr)
Ville:	Roubaix
Région:	Nord-Pas-de-Calais
ISP:	OVH SAS

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Date:	Sun, 07 Oct 2018 12:17:19 GMT
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company about us partners distributors history calixar’s business model technology & approach mission technology case studies track record pipeline gpcr ion channels transporters vaccines products customized detergents purified membrane proteins services platform qualify your expression system contact us locations job offer information request media news press releases related news events a world reference in native membrane proteins isolation from the gene... ... to the 3d structure production of native membrane proteins expression in multiple systems extraction & stabilization purification of functional targets crystallization & structure determination preserving the nature of your membrane proteins... ... to improve drug, antibody and vaccine discovery previous next membrane proteins isolation process : calixar technology calixar offers a unique and patented technological platform allowing to isolate in solution – with the highest purity levels – full-length membrane proteins , while keeping their structural and functional integrity. our approach represents the opportunity for pharmaceutical companies to start and work with high quality targets or antigens before developing antibodies, formulating vaccines and/or discovering a primary lead through structure based drug design or high throughput screening assays. know more about us membrane proteins extraction and production calixar’s approach allows to preserve the original structure and function of membrane proteins (gpcrs, ion channels, transporters, receptors, anchors and viral proteins) providing solutions for pharmaceutical industries, biotechnology companies and academic teams to develop conformational antibodies, formulate new vaccines, carry out structure based drug discovery and/or hts assays. moreover, the expertise is also specifically adapted to downstream processing (dsp) as well as upstream processing (usp – expression part). membrane proteins represent more than 60% of all therapeutic targets. however only 1 percent of the 3d structures were solved mainly with mutations… the real challenge with membrane proteins is to produce and isolate them in a native conformation without mutations or deletions and with high purity in solution . conventional approaches tend to affect the membrane proteins integrity forcing researchers to use bypass methods such as refolding or mutagenesis or not enough pure scaffolds systems. to overcome this crucial issue, our company develops new tools and protocols for the deorphanization, identification, expression, extraction, purification, stabilization, structural functional characterization, crystallization of membrane proteins as well as detergent quantification. the starting biological material (virus, bacteria, primary cells, organs,…) can be endogenous or recombinant systems. calixar uses original, innovative and customized chemistry that aims to adapt to the biochemical characteristics of the target during the solubilization/ purification/stabilization steps. calixar news novel innovative detergent family for membrane-protein extraction chem2stab, the common research laboratory created by the university of avignon (france) and calixar, announces the publication of a new article by g. durand’s laboratory (nyame g. et al., 2018, methods). 11 july 2018 new publication on native gpcr stabilization calixar announces the publication of a new article in scientific reports – nature entitled “enabling nmr-based fragment screening using stabilized native gpcr”. (igonet et al., 2018) 28 may 2018 calixar best inventing french-tech company 2018 calixar named best inventor 2018 of the french auvergne-rhône region among french-tech start-up companies. 16 may 2018 press releases calixar and astrazeneca to publish new insight on kcc2 architecture and function in scientific reports 28 november 2017 events novalix conference - 13-15 june 2018 calixar selected to present at the 5th novalix conference "biophysics in drug discovery 2018. 6 june 2018 calixar – headquarters bâtiment laennec 60 avenue rockefeller 69008 lyon france tel: +33 481 076 460 fax: +33 481 076 469 contact(at)calixar.com calixar – joint research lab creativa – pépinière d’entreprises bâtiment a 200 rue michel de montaigne site agroparc – bp 21221 84911 avignon cedex 9 france contact(at)calixar.com calixar – north america partner office 185 alewife brook parkway, #410 cambridge, ma 02138 usa contact(at)calixar.com calixar – asia partner office ccifj iida bldg 2f, 5-5 rokubancho, chiyoda-ku, tokyo 102-0085 〒102-0085 東京都千代田区六番町５−５飯田ビル japan contact(at)calixar.com copyright © - legal notice - site map - calixar all rights reserved. powered by arthesis

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Domain Name: calixar.com
Registry Domain ID:
Registrar WHOIS Server: whois.nordnet.net
Registrar URL: http://www.nordnet.net
Updated Date: 2017-06-12T07:42:29.0Z
Creation Date: 2009-06-22T07:33:22.0Z
Registrar Registration Expiration Date: 2018-06-21T22:00:00.0Z
Sponsoring Registrar: NORDNET
Sponsoring Registrar IANA ID: 68
Registrar Abuse Contact Email: abuse-registrar@nordnet.net
Registrar Abuse Contact Phone: +33.969360360
Domain Status: clientTransferProhibited http://www.icann.org/epp#clientTransferProhibited
Registry Registrant ID:Not Available From Registry
Registrant Name: Dejean Emmanuel
Registrant Organization: Calixar
Registrant Street: Chez Ibcp
Registrant Street: 7 Passage du Vercors
Registrant City: Lyon
Registrant State/Province:
Registrant Postal Code: 69367
Registrant Country: FR
Registrant Phone: +33.437652939
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Registrant Fax:
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Registrant Email: edejean@calixar.com
Registry Admin ID:Not Available From Registry
Admin Name: Dejean Emmanuel
Admin Organization: Calixar
Admin Street: 60 Avenue Rockefeller
Admin City: Lyon
Admin State/Province:
Admin Postal Code: 69008
Admin Country: FR
Admin Phone: +33.481076460
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Admin Email: edejean@calixar.com
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Tech Name: Contact Technique Lri
Tech Organization: Nordnet
Tech Street: 111 Rue de Croix
Tech City: Hem
Tech State/Province:
Tech Postal Code: 59510
Tech Country: FR
Tech Phone: +33.892702033
Tech Phone Ext:
Tech Fax: +33.320665669
Tech Fax Ext:
Tech Email: technical@lerelaisinternet.com
Name Server: ns3.lerelaisinternet.com
Name Server: ns4.lerelaisinternet.com
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